Rendas-Baum R, Baranwal N, Joshi AV, Park J, Kosinski M. J Patient Rep Outcomes. Liang MH
, Roberts WN
IgM) on attainment PhGA. Stojan G
Tel: 03 88 12 84 74; Fax: 03 88 12 82 90; E-mail: Measuring disease activity in adults with systemic lupus erythematosus: the challenges of administrative burden and responsiveness to patient concerns in clinical research, Patterns of disease activity in systemic lupus erythematosus, Novel evidence-based systemic lupus erythematosus responder index, Reliability and validity of six systems for the clinical assessment of disease activity in systemic lupus erythematosus, Failure to achieve lupus low disease activity state (LLDAS) six months after diagnosis is associated with early damage accrual in Caucasian patients with systemic lupus erythematosus, Treatment target in newly diagnosed systemic lupus erythematosus, 10 most important contemporary challenges in the management of SLE, Measurement of systemic lupus erythematosus activity in clinical research, Definition, incidence, and clinical description of flare in systemic lupus erythematosus. In 32 studies, disease activity measured by PGA was compared with changes in laboratory markers, with the aim of correlating clinical and serological features [9, 21, 30, 32, 34, 3739, 44, 45, 48, 49, 55, 5861, 63, 64, 66, 67, 69, 71, 74, 75, 82, 86, 89, 9194]. Cloud, mobility, security, and more. , Devilliers H
, ODell JR
The index has proved quick and easy to use despite a comprehensive database and compares favourably with . Mok CC
Oxford Textbook of Neuropsychiatry - 2020 | PDF | Psychiatry TOTAL DOCUMENTS. [PDF] Use of Physician Global Assessment in systemic lupus ~SLE~. The last MEDLINE search was performed on 1 July 2019. , Gladman DD. , Chang AY
We analysed the performance of the SELENA SLEDAI Physician's Global Assessment (SSPGA) and the Lupus Foundation of America-Rapid Evaluation of Activity in Lupus (LFA-REAL) as measures . All versions are validated and used by lupus researchers for clinical and research purposes. Criterion validity also refers to the degree to which an instrument predicts aspects and phenomena occurring in the future [108]. CLOSED ANGLE/ ANGLE CLOSURE GLAUCOMA. Published by Oxford University Press on behalf of the British Society for Rheumatology. , Mokkink LB
Changes in the PGA correlated with changes of other disease activity indices (SLEDAI, SLAM, LAI, patient global assessment), laboratory exams (ESR), patient-reported outcomes (Lupus Impact Tracker) [23, 50, 58, 77, 78, 81, 83] and response to treatment [4]. Clipboard, Search History, and several other advanced features are temporarily unavailable. BICLA responders had fewer lupus-related serious . , Petri MA
Forbess LJ
Liang et al. , Sjwall C. Strand V
Reliability. Oxford Textbook of. The aim of this systematic literature review (SLR) is to describe and analyse the psychometric properties of PGA. In our centre, new tools for the assessment of SLE activity: the Lupus Activity Scoring Tool (LAST) and Clinical Lupus Activity Scoring Tool (C-LAST) were developed and validated. et al. , Block JA
Pincus and colleagues conducted a study of . , Rairie JE
It was published in 1977 and was initially designed for the measurement of self-assessed pain in rheumatoid arthritis although it has since been used to evaluate RA more globally. The other authors have declared no conflicts of interest. Sullivan KE
Assessing disease activity in rheumatic diseases such as systemic lupus erythematosus (SLE) is vital for effective treatment. , Lin M
Annapureddy N
1 2. et al. The random effects model gives a more conservative estimate considering the heterogeneity. et al. For your privacy and protection, when applying to a job online, never give your social security number to a prospective employer, provide credit card or bank account information, or perform any sort of monetary transaction. The Janus kinase (Jak)/signal transducer and activating protein (STAT) pathways mediate the intracellular signaling of cytokines in a wide spectrum of cellular processes. The Physician Global Assessment (PGA) of treatment response measures the overall response to treatment as assessed by the physician. Petri M
The interRR was assessed in seven studies [4, 10, 11, 36, 65, 68, 94], showing values ranging from 0.67 [68] to 0.96 [94]. . , Wallace DJ
Over the years, PGA-IGA scales were modified for the purpose of clinical settings and thus present a diversity in the number of response options (4 to 10 points), the response options label and the . LECTURE 10: MEDICAL SURGICAL NURSING. [9] for a disease activity index scored on a VAS ranging from 0 to 3, with an increase of 1.0 since the last visit indicating a flare. Montreal, Canada Area. Psychometric properties data were analysed according to the OMERACT Filter methodology version 2.1. Faculty Publications: Feb. 23-March 2 The Physician Global Assessment (PGA) is an important tool for assessing disease activity in lupus. Touma Z
, Criscione-Schreiber LG
et al. Navarra SV
Different scores and lengths of visual evaluation were employed: the first was the 010 VAS suggested by Liang et al. (Open Access) Development and assessment of a computerized index of [35], the PGA correlated, although moderately, with the need for treatment change (r=0.46, P<0.01). sharing sensitive information, make sure youre on a federal One study showed a significant ability of the PGA in distinguishing between patients (P<0.0001) and observers (P<0.0001), but not between visits [79]. The PGA is a valid instrument but has variable reliability; its scoring should be standardized. , Liberati A
In the second column, the definitions were reported according to the VAS used in the study. et al. Laboratory Investigation Results Influence Physician's Global , Birmingham DJ
PDF Getting To Know Dr. Derek Shendell, New Safe Schools Project Director Piga M
Patient global assessment in measuring disease activity in rheumatoid , Ravelli A
Responsiveness, or sensitivity to change, is the usefulness of a test to detect minimum clinically important differences [20, 109]. The measurements were in the form of a scale from 0 to 3 in 54 studies [2, 3, 9, 10, 12, 13, 21, 2469, 103], a 010 scale in 12 studies [4, 60, 7079], a 0100 scale in 9 studies [27, 40, 78, 8085], a 07 Likert scale [11, 78, 80], a 02 scale [53], a 04 scale [86] and a 05 scale [87]. et al. Feasibility is the ease of application of the instrument of measure in its intended setting [106]. An international panel of 79 SLE experts participated in a three-round Delphi consensus . If you have a published paper from this period that does not appear on this list, please contact Sue Marone, who will add it to next week's collection. Beaton DE
et al. Genetic linkage has related dysfunction of . Mok CC
They proposed a physician global score on a 10cm visual analogue scale (VAS) to be used as a gold standard to compare six disease activity instruments [4]. et al. , Navarra SV
doi: 10.1136/rmdopen-2022-002395. , Hambleton IR
, Dyer JW
et al. It is unclear when or with what justification the physician global assessment of disease status (PhGA) was first used to assess patients with systemic . , Urowitz MB
Federal government websites often end in .gov or .mil. , Schirmbeck LA
The following search strategy was used through MEDLINE via PubMed: (((lupus erythematosus, systemic[MeSH Terms] OR (lupus[TIAB] AND erythematosus[TIAB] AND systemic[TIAB]) OR systemic lupus erythematosus[TIAB] OR (systemic[TIAB] AND lupus[TIAB] AND erythematosus[TIAB]))) OR SLE[TIAB]) AND (physician global assessment[TIAB] OR PGA[TIAB]). Physician Global Assessment International - ScienceDirect Thousand Oaks. Three studies evaluated the association between PGA scores and treatment changes: PGA correlated negatively with adherence to treatment assessed through an item scale (r=0.31, P=0.11) [34]; clinically defined mild and moderate flares had a higher disease activity by the PGA (P<0.001) than those defined as mild/moderate flare only by medication changes [55]; PGA scores were associated positively with response to belimumab treatment (P=0.039) [43]. Higher disease activity is an important predictor of both organ damage and mortality [2] and the attainment of low disease activity is associated with a reduction in early damage [5, 6]. , Wallace DJ
, Matos A
In a post-hoc analysis of phase 3 belimumab trials, improvements and no worsening in the PGA were greater among SRI responders vs SRI non-responders (P<0.001) [52]. , Saad-Magalhes C
et al. et al. PDF Physician global assessments for disease activity in rheumatoid et al. , Koutsoviti S
, Borghoff K
2022 Sep;8(2):e002395. A validation study of the SRI for juvenile SLE [60] showed that exclusion of the BILAG or PGA from the SRI did not change the accuracy of the SRI in detecting improvement. A multi-item Physician Global Assessment scale to assess psoriasis Bethesda, MD 20894, Web Policies , Holland M
, Flower C
RMD Open 2018;4:e000578. The geographical analysis of the Global Global Respiratory Devices market provided in the report is just the right tool that competitors can use to discover untapped sales and business expansion . Physician Global Assessment to Track Outcomes - JAMA , Seaman AL
Gandhi N
Copay AG
, Su J
, Ibanez D
, Klein-Gitelman MS
PGA or SGA described in ePROVIDE - Mapi Research Trust SFI, LLDAS, SRI, Definitions of Remission in Systemic Lupus Erythematosus remission criteria) [3, 5, 10, 1315, 104]. , Landis RC
In the absence of a well-recognized gold standard for disease activity, criterion validity of the PGA is established when it correlates with a measure that the author of the study defined a priori as the gold standard. , Magder LS
Patient global assessment (PGA) is one of the most widely used PROs in RA practice and research and is included in several composite scores such as the 28-joint Disease Activity Score (DAS28). Management of systemic lupus erythematosus (SLE) often depends on disease severity and disease manifestations, [] although hydroxychloroquine has a central role for long-term treatment in all SLE patients. No study has evaluated the feasibility of the PGA in SLE to date. A high variability in scales was found, causing a wide range of reliability (intraclass correlation coefficient 0.670.98). . , Nguyen SC
Methods This SLR was conducted by two independent reviewers in accordance with the PRISMA statement. Ensure second line of defense Derivatives RWA reviews are performed consistently and . et al. Physician global assessment in systemic lupus erythematosus: can we PGA is often assessed by a single question with a 0-10 or 0-100 response. T2 - A longitudinal study. , Leung HW
The interrater reliability (interRR) of the PGA is the ability to provide consistent scores in a stable population between two or more physicians who evaluate the disease activity of the same patient. AU - Kasitanon, Nuntana. In 11 retrieved studies [10, 13, 33, 36, 45, 48, 50, 55, 56, 65, 96] the PGA was part of the SFI [104] and in 10 studies [3, 29, 40, 46, 52, 60, 69, 80, 94, 98] it was part of the SRI [3] (both discussed in the Responsiveness section). , Hearth-Holmes M. Khan A
, Jolly M. Mok CC
, Hochberg M. Wallace DJ
The content can vary and relates either to global health (e . On stratifying the results by individual clinician, values ranged from 0.61 to 0.90, except for those reported by . Associations between physicians' global assessment of disease activity Observed and articulated management issues and responses. et al. et al. , Garabajiu M
The Validity of Patient and Physician Global Disease Activity Even though the PGA showed optimal reliability, a very low interRR for flare using the PGA (ICC=0.18) was found in a single study [65] compared with that of the BILAG (ICC=0.54) or SFI (ICC=0.21). PGA is a valid, responsive and feasible instrument, while its reliability was impacted by the scale adopted, suggesting the major need for a standardization of its scoring. , Petri M. Isenberg DA
The PGA was integrated in composite indices, including the definition of the LLDAS [12, 13, 29, 34, 37, 39, 40] and remission [29, 37] (Table1). , Vogel-Claussen J
Brunner HI
Physician global assessment in systemic lupus erythematosus: Can we This concept includes content validity, face validity, construct validity and criterion validity. Wells GA
Schneider M
, Sadovici-Bobeica V
Criterion validity. While specific studies remain to be performed to determine the optimal method for scoring the PGA, this literature search showed that the most adopted form of PGA was a 10cm 03 VAS with anchors (0, none; 1, mild; 2, moderate; 3, severe activity) [3]. Reliability measures the reproducibility of the instrument: it refers to the degree of agreement between different observers (interrater) and in the same observer over time (intrarater). , Mikolaitis-Preuss RA
Tyk2 Targeting in Immune-Mediated Inflammatory Diseases , Bresee C
et al. The aim of this systematic literature review is to describe and analyse the psychometric properties of the PGA. Mina R
2022 Jan 11;11(2):340. doi: 10.3390/jcm11020340. Touma Z
Thank you for submitting a comment on this article. , Morabito LM
Intoduction to X 20 - Physician Global Assessment For instance, in an analysis of studies of the prevalence of SLE in the Asia-Pacific region, higher rates of renal involvement were observed in Asian patients (21-65% at SLE diagnosis and 40 . This week's edition of Faculty Publications includes Cedars-Sinai studies that were published Feb. 23-March 2. Chaigne B
, Gallacher AE
Methods We determined the variability of MD globals, surveying rheumatologists from the Canadian Rheumatology Association using rheumatoid . Currently the lack of standardized scoring, as well as the subjectivity of the physician judgements, can be an important source of heterogeneity, especially in trials. In this systematic review we have analysed the measurement properties of the PGA, including the validity, reliability, responsiveness and feasibility. Unauthorized use of these marks is strictly prohibited. Liang MH
It operates in Albuquerque, and New Mexico. Newark, New Castle, USA, March 03, 2023 (GLOBE NEWSWIRE) -- The global complement-targeted therapeutics market is expected to grow at a CAGR of 8.9% from 2022 to 2030, owing to the rising . Associations between physicians' global assessment of disease activity In support of its face validity, the PGA was used to define the disease activity score in all 91 studies retrieved by the literature search, having a role as an outcome measure as well as a comparator to assess the validity of other indices. et al. In Fatemi et al. , Engel SM
et al. Search for other works by this author on: Rheumatology Unit, AOU University Clinic and University of Cagliari, Department of Medical Sciences and Public Health, Cagliari, Italy, Centre Hospitalier Universitaire de Dijon, Hpital Franois-Mitterrand, service de mdecine interne et maladies systmiques (mdecine interne, 2) et Centre dInvestigation Clinique, Service de rhumatologie, Hpitaux Universitaires de Strasbourg, Universit de Strasbourg, Centre National de Rfrence des Maladies Systmiques et Autoimmunes Rares Est Sud-Ouest (RESO). European League Against Rheumatism. , Longenecker JC
Epub 2014 Jul 10. The site is secure. , Petri MA
Would you like email updates of new search results? , Socher SA
. Methods Patients attending a rheumatology clinic between 2013 and 2017 completed specific (SLEQOL) and generic (SF36) health-related quality of life (HRQoL) surveys and rated . Of note, it is not trivial that we found a good convergent validity with other instruments (SLEDAI, BILAG, LAI, SLAM and ECLAM) [10, 23, 24, 26, 28, 29, 35, 54, 68, 76, 84, 99]. , Chatzidionysiou K
The aim of this systematic literature review (SLR) is to describe and analyse the psychometric properties of PGA. Compared with nonresponders, BICLA responders had greater improvements in global and organ-specific disease activity (Physician's Global Assessment, SLE Disease Activity Index 2000, Cutaneous Lupus Erythematosus Disease Area and Severity Index Activity, and joint counts; all nominal P < 0.001). SLE or at an SLE site, but only if the injury requires treatment by a licensed medical doctor. Injuries requiring medical treatment are considered to be "reportable incidents," and must be reported to the NJDOE within five working days of the occurrence. Objective: To examine the feasibility of using Physician Global Assessment (PGA) scores to collect and track patient acne and . , Sato JO
, Esdaile JM. All clinical diagnoses were verified by review of the patients' inpatient and outpatient files at the time of capillaroscopy. Content validity pertains to the degree to which the instrument measures all facets of a construct of interest [20]: this property is satisfied if the PGA is considered able to measure all aspects of disease activity in SLE in a comprehensive way. , Bouter LM
Brunner HI
Systemic lupus erythematosus (SLE), is the most common type of lupus. , Glassman DS
Clinical Trial Physician - Rheumatology Job in San Diego, CA - Bristol
Liquor License Lookup Wisconsin,
Triple Nine Society Sat Score,
Articles P
