What Are Side Effects of the COVID-19 Vaccines? Parrino D, Frosolini A, Gallo C, De Siati RD, Spinato G, de Filippis C. Tinnitus following COVID-19 vaccination: report of three cases. 2021. https://doi.org/10.1016/j.nrleng.2021.05.002. Notghi AA, Atley J, Silva M. Lessons of the month 1: Longitudinal extensive transverse myelitis following AstraZeneca COVID-19 vaccination. COVID Vaccine Side Effects | Johns Hopkins Medicine Google Scholar. The chances of any of these side effects occurring after vaccination differ according to the specific vaccine. Why 25-50% of vaccine side-effects are 'anxiety-related and not a result of Covid jab' Anxiety-related reactions comprise symptoms such as vasovagal reaction, when a stressful trigger the sight of blood or syringe causes someone to feel dizzy or faint. COVID-19 vaccination also affects the cranial and peripheral nerves and causes side effects such as Bell's palsy (facial nerve palsy7 cranial nerve), abducens nerve palsy (lateral rectus ocular muscle nerve palsy6 cranial nerve), impaired vision, olfactory, hearing, GuillainBarre syndrome (GBS), small fiber neuropathy, ParsonageTurner syndrome, and also herpes zoster. The problem occurs more often in adolescents (teens) and young adults, and in males. Investigators note that people with this syndrome tend to experience increased post-traumatic stress, general stress, anxiety, health anxiety, and suicidal ideation. QJM: An Int J Med. https://www.cdc.gov/coronavirus/2019-ncov/long-term-effects/post-covid-appointment/index.html. J Thromb Haemost. Heart problems are a very rare side effect of COVID-19 vaccines. Accessed May 6, 2022. Abraham G, Bhalala OG, de Bakker PI, Ripatti S, Inouye M. Towards a molecular systems model of coronary artery disease. Coronavirus disease 2019 and cardiovascular complications: Focused clinical review. On the other hand, women have the highest incidence of neurological complications because they induce a stronger immune response against foreign antigens, which can lead to the targeting of self-antigens and lead to autoimmune disorders [9]. Adolescents have higher rates of syncope after vaccination. We don't know why that is, how long these symptoms will last or if there are effective ways to treat them. Most side effects stop within 48 hours. panic attacks, nausea, or sweats; palpitations; fainting (due to a reflex in which pain or the sight of blood triggers a drop in blood pressure) . Waheed S, Bayas A, Hindi F, Rizvi Z, Espinosa PS. VAERS reports of syncopal events occurring after receipt of any influenza vaccine administered to persons aged 18 years during the 201920 influenza season (i.e., July 1, 2019June 30, 2020) served as a comparison, because influenza vaccine is similarly administered as a single dose and is available to all U.S. adults. COVID-19: Evaluation and management of adults following acute viral illness. Anxiety-related events, including syncope, occurring soon after COVID-19 vaccination could raise concern among other vaccine recipients and staff members, particularly in a mass vaccination setting. Wichova H, Miller ME, Derebery MJ. 2021;358: 577661. Geneva, Switzerland: World Health Organization; 2019. PubMed endorsement of these organizations or their programs by CDC or the U.S.
CDC twenty four seven. FDA says Guillain-Barre syndrome is possible risk of Pfizer RSV vaccine 32 Havla J, Schultz Y, Zimmermann H, Hohlfeld R, Danek A, Kmpfel T. First manifestation of multiple sclerosis after immunization with the Pfizer-BioNTech COVID-19 vaccine. However, in order to prove the effectiveness of the vaccine in terms of safety and side effects, the implementation of phase 4 of clinical studies is necessary. Guillain-Barr syndrome after COVID-19 vaccine: should we assume a causal Link? Provided by the Springer Nature SharedIt content-sharing initiative. Despite concerns over Covid vaccines, most side effects occur with hours or weeks of having a jab. Reporting rates were calculated using the approximate number of doses of each vaccine administered during the respective analysis periods. Descriptive analyses of VAERS data were stratified by vaccine type, sex, and age group. A third reported fever or chills, and about a fifth said they were nauseous. Why 25-50% of vaccine side-effects are 'anxiety-related - ThePrint JAAD Case Rep. 2021;15:601. What Are Side Effects of COVID-19 Vaccines? - Health The majority -- 61% -- were women, the median age was 36 years and 20% of the patients told vaccination site staff they had a history of fainting associated with receiving injections or an aversion to needles. Angana Chakrabarti 25 July, 2021 12:01 pm IST part 46, 21 C.F.R. 13 days after the moderna vaccine (3/15) I began to have dizzy spells and panic attacks at work. People who had severe illness with COVID-19 might experience organ damage affecting the heart, kidneys, skin and brain. To prepare for your appointment, write down: Your health care provider might do lab tests, such as a complete blood count or liver function test. Vaccine providers should be aware of anxiety-related events after vaccination and observe all COVID-19 vaccine recipients for any adverse reactions for at least 15 minutes after vaccine administration. Finsterer J, Redzic Z. Symptomatic peduncular, cavernous bleeding following SARS-CoV-2 vaccination induced immune thrombocytopenia. See I, Su JR, Lale A, et al. Clark RT, Johnson L, Billotti J, Foulds G, Ketels T, Heard K, Hynes EC. A panel of experts at the virtual American Academy of Allergy, Asthma and Immunology Annual Meeting highlighted current evidence on allergic reactions to available COVID-19 vaccines and how to. 2021. https://doi.org/10.2139/ssrn.3841558. PubMed Curr Cardiol Rep. 2014;16(6):110. 2021. https://doi.org/10.1136/jnnp-2021-327027. Acute attack in a patient with multiple sclerosis 2 days after COVID vaccination: a case report. 241(d); 5 U.S.C. Transverse myelitis is an inflammation of a part of the spinal cord that usually occurs after infection and is associated with impaired sensory, motor, and autonomic function (bladder and intestines) in areas below the area of inflammation in the spinal cord. 2021;1: 100019. Acta Neurol Belg. Muscle Nerve. 2021;121: 102662. BMJ Case Reports CP. One study published by the CDC reports that from March 2020 to January 2021, patients with COVID-19 had nearly 16 times the risk for myocarditis compared with patients who did not have COVID-19. Anxiety-related adverse events following immunization (AEFI): a systematic review of published clusters of illness. IDCases. 2021;384(23):220211. In nucleic acid and adenovirus-based vaccines, fragments of the virus mRNA or genome enter human cells and induce the production of viral proteins [3]. Liu BD, Ugolini C, Jha P. Two cases of post-Moderna COVID-19 vaccine encephalopathy associated with nonconvulsive status epilepticus. As a follow-up to these interviews, CDC analyzed reports of syncope shortly after receipt of Janssen COVID-19 vaccine to the Vaccine Adverse Event Reporting System (VAERS), the vaccine safety monitoring program managed by CDC and FDA. Allergic reactions to COVID-19 vaccines rare, but 'a lot of - Healio Each vaccine's clinical trial had 30,000-40,000 participants and was required to produce data for at "least two months after completion of the full vaccination regimen to help provide adequate . Some people continue to experience health problems long after having COVID-19. Sudden onset of myelitis after COVID-19 vaccination: an under-recognized severe rare adverse event. Neurology. State and local health departments that participated in this investigation. Another CDC report released Friday looked at side effects reported by more than 300,000 J&J vaccine recipients. These activities were reviewed by CDC and were conducted consistent with applicable federal law and CDC policy.. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. Recognizing vaccine-induced immune thrombotic thrombocytopenia. https://www.cdc.gov/coronavirus/2019-ncov/hcp/clinical-care/post-covid-conditions.html. Neuropsychiatr Dis Treat. Read on to find out which COVID vaccine side effect is an indicator of a "very robust immune response," according to doctors, and for more side effects to expect, check out The One Side Effect . #BestPractices. 2021;208: 106887. Article The most important and most common complications are cerebral venous sinus thrombosis (more about AstraZeneca), transverse myelitis (more about Pfizer, Moderna, AstraZeneca, and Johnson & Johnson), Bell's palsy (more about Pfizer, Moderna, AstraZeneca), GBS (more about Pfizer, AstraZeneca, and Johnson & Johnson), and the first manifestation of MS (more about Pfizer). Finsterer J, Scorza FA, Scorza CA. The reporting rates of syncope to VAERS after Janssen COVID-19 and influenza vaccines (201920) were 8.2 and 0.05 per 100,000 doses, respectively. Pandemic Drove Spike in Panic Attacks Other side effects can include pain, redness or swelling at the injection site and possibly headache or nausea, the US Centers for Disease Control and Prevention said. panic attacks after vaccine : r/CovidVaccineEffects - reddit For some people, the second [] Panic Disorder | Johns Hopkins Medicine Nagy A, Alhatlani B. Cookies used to make website functionality more relevant to you. COVID-19: Long-term effects - Mayo Clinic Important: If you are experiencing a medical emergency, seek immediate assistance from a healthcare provider or call 9-1-1. S Vaccine. Vaccines. 2021. https://doi.org/10.7759/cureus.13426. Case Rep Infect Dis. QJM: An Int J Med. The largest proportion of reported syncopal events after Janssen COVID-19 vaccination occurred among persons aged 1829 years and decreased in increasing age groups. This will affect how neurons function and cause the infected to be more susceptible to anxiety and depression. Post-COVID conditions: Overview for healthcare providers. CDC is not responsible for the content
FDA adds new warning on Johnson & Johnson vaccine related to rare The Lancet. Likewise, some mass vaccination sites had more information available than did others. Questions or messages regarding errors in formatting should be addressed to
i had been worried about it beforehand but not to the point where i had an attack. Although four of the five mass vaccination sites that reported anxiety-related events temporarily suspended COVID-19 vaccination, none of the reports to VAERS was considered serious. But as I sat for the required 15 minutes of observation time, a wave of something engulfed my body. Multisystem inflammatory syndrome in children (MIS-C), Safe outdoor activities during the COVID-19 pandemic, Safety tips for attending school during COVID-19, Advertising and sponsorship opportunities, Symptoms that get worse after physical or mental effort, Lung (respiratory) symptoms, including difficulty breathing or shortness of breath and cough, Neurological symptoms or mental health conditions, including difficulty thinking or concentrating, headache, sleep problems, dizziness when you stand, pins-and-needles feeling, loss of smell or taste, and depression or anxiety, Heart symptoms or conditions, including chest pain and fast or pounding heartbeat, Digestive symptoms, including diarrhea and stomach pain, Blood clots and blood vessel (vascular) issues, including a blood clot that travels to the lungs from deep veins in the legs and blocks blood flow to the lungs (pulmonary embolism), Other symptoms, such as a rash and changes in the menstrual cycle, You had certain medical conditions before getting the, You had a condition affecting your organs and tissues (multisystem inflammatory syndrome) while sick with. Introna A, Caputo F, Santoro C, Guerra T, Ucci M, Mezzapesa DM, Trojano M. Guillain-Barr syndrome after AstraZeneca COVID-19-vaccination: a causal or casual association? In clinical trials, two participants in their . On April 30, 2021, this report was posted online as an MMWR Early Release. Assiri SA, Althaqafi RM, Alswat K, Alghamdi AA, Alomairi NE, Nemenqani DM, Ibrahim ZS, Elkady A. Are people having more panic attacks in the COVID era? These viral proteins are eventually identified as antigens and stimulate antibody production. Department of Health and Human Services. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. Scully M, Singh D, Lown R, Poles A, Solomon T, Levi M, Goldblatt D, Kotoucek P, Thomas W, Lester W. Pathologic antibodies to platelet factor 4 after ChAdOx1 nCoV-19 vaccination. Can Anxiety Impact The Efficacy Of Covid-19 Vaccines? - Outlook On April 7, 2021, after 5 weeks use of the Janssen COVID-19 vaccine under the Food and Drug Administration (FDA) Emergency Use Authorization (EUA), CDC received reports of clusters of anxiety-related events after administration of Janssen COVID-19 vaccine from five mass vaccination sites, all in different states. Fatigue. 2021;80:34852. Panic attacks every time I try to get the Covid vaccine Terrified of needles? That can affect your health CAS I would encourage you to give us a call on the Beyond Blue Support Service; we're available 24/7 by phone on 1300 22 4636. A MedDRA coded event does not indicate a medically confirmed diagnosis. J Neurol. ), or your upcoming vacation. 5 "Red Flags" After Your COVID Vaccine Eat This Not That It is important that vaccination providers are aware that anxiety-related adverse events might be reported more frequently after receipt of the Janssen COVID-19 vaccine than after influenza vaccination and observe all COVID-19 vaccine recipients for any adverse reactions for at least 15 minutes after vaccine administration. Symptoms of long COVID. Dyer O. Covid-19: Regulators warn that rare Guillain-Barr cases may link to J&J and AstraZeneca vaccines. Report an Adverse Event using the VAERS online form or the downloadable PDF. If you have never had COVID-19, you may notice more side effects after the second dose than after the first dose. 2021;14:349. . PubMed Central Due to potential blood clots following administration of the Johnson & Johnson vaccine, the CDC updated its recommendations in December 2021. 2021;42(11):43979. Ahmed SH, Waseem S, Shaikh TG, Qadir NA, Siddiqui SA, Ullah I, Waris A, Yousaf Z. SARS-CoV-2 vaccine-associated-tinnitus: a review. Possible side effects: Pain, redness, or swelling at the site where the shot was administered, and/or tiredness, headache, muscle pain, chills, fever, or nausea throughout the rest of the body. In addition, you might benefit from connecting with others in a support group and sharing resources. Covid-19 vaccine side effects: Why you shouldn't freak out of these Because the Janssen COVID-19 vaccine is administered as a single dose, this vaccine might be a more attractive option for persons who have needle aversion. Google Scholar. Inflammation and problems with the immune system can also happen. Syncope after vaccinationUnited States, January 2005July 2007. The Covid-19 Vaccine Safety Technical (VaST) Work Group confirmed "data available to date suggest likely association" of myocarditis and pericarditis in people who get the Pfizer and Moderna jabs. PubMedGoogle Scholar. COV2.S vaccination. Article Recommendations for observation after COVID-19 vaccine administration are available at https://www.cdc.gov/vaccines/covid-19/info-by-product/clinical-considerations.html. Other types of side effects from the coronavirus vaccines are not unusual. Kohli S, Varshney M, Mangla S, Jaiswal B, Chhabra PH. Post-COVID-19 syndrome. Updated recommendations from the Advisory Committee on Immunization Practices for use of the Janssen (Johnson & Johnson) COVID-19 vaccine after reports of thrombosis with thrombocytopenia syndrome among vaccine recipientsUnited States, April 2021. 45 C.F.R. Neurological symptoms and neuroimaging alterations related with COVID-19 vaccine: Cause or coincidence? For all four vaccines, pain at the injection. Tahir N, Koorapati G, Prasad S, Jeelani HM, Sherchan R, Shrestha J, Shayuk M. SARS-CoV-2 vaccination-induced transverse myelitis. McGonagle D, De Marco G, Bridgewood C. Mechanisms of immunothrombosis in vaccine-induced thrombotic thrombocytopenia (VITT) compared to natural SARS-CoV-2 infection. Typical side effects may include swelling or pain at the point of injection, tiredness, fever or headache, as well as muscular. 2021;17(10):34813. Patient tips: Healthcare provider appointments for post-COVID conditions. 2021. https://doi.org/10.1002/alr.22809. How well do face masks protect against COVID-19? Brain Hemorrhages. Syncopal events after influenza vaccination were reported most frequently among persons aged 1829 years; the median patient age was 26 years (range=1888 years). provided as a service to MMWR readers and do not constitute or imply
Article Some symptoms are similar to those caused by chronic fatigue syndrome and other chronic illnesses that develop after infections. COVID-19 vaccine-induced encephalitis and status epilepticus. Supportive care included placing the person supine and offering hydration and food. Each type of vaccine can play a different role in increasing the risk of manifestation of these disorders (Tables 2, 3). Int J Res Pharma Sci. Side effects and perceptions following Sinopharm COVID-19 vaccination. One hundred twenty-three (19%) reports indicated that the recipient had a history of syncope associated with receiving injections or needle aversion. Finally, the Janssen COVID-19 vaccine was not directly compared with other currently available COVID-19 vaccines and instead was compared with influenza vaccine administered during the 201920 season. Post-COVID-19 syndrome involves a variety of new, returning or ongoing symptoms that people experience more than four weeks after getting COVID-19. Therefore, it is possible that some persons seeking Janssen COVID-19 vaccination could be more highly predisposed to anxiety-related events after being vaccinated. Comput Struct Biotechnol J. J Neurol. now i keep having panic attacks, even though i'm not panicking about anything. Crit Care Med. Among people age 65 and older, 1 in 4 has at least one medical condition that might be due to COVID-19. Learn more about COVID-19 vaccine safety. Who Had Serious Side Effects from Covid 19 Vaccine? "We don't know why that is, how long these symptoms will last or if there are effective ways to treat them. chills . Bell's palsy and small fiber neuropathy are more commonly observed in mRNA-based vaccines [63, 64]. Ramasamy MN, Minassian AM, Ewer KJ, Flaxman AL, Folegatti PM, Owens DR, Voysey M, Aley PK, Angus B, Babbage G. Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial. Int Med Case Rep J. i had my 2nd covid vaccine on friday and about 20 mins after i had the biggest panic attack i've experienced in almost 2 years. Ramsay Hunt syndrome following COVID-19 vaccination. 2021;25(5):3023. Thirteen (20%) patients informed staff members of a history of fainting associated with receiving injections or needle aversion. Springer Nature. AskMayoExpert. Chills and swollen lymph nodes can also occur. If you had COVID-19 before being vaccinated, the first injection may cause more noticeable side effects than for people who have not had the coronavirus. This content does not have an Arabic version. * CDC reviewed reports to the Vaccine Adverse Events Reporting System that contained the Medical Dictionary for Regulatory Activities preferred terms syncope or syncope vasovagal for all Janssen COVID-19 vaccines administered during March 2April 12, 2021, and any influenza vaccine administered to an adult aged 18 years during July 1, 2019June 30, 2020. At the same time, there are many reports of side effects after getting a COVID-19 vaccine. In addition, skin blisters have been observed in the ear area, leading us to hypothesize that reactivation of VZV could be a cause for RHS as well as Bell's palsy [71]. Syncope and seizures following human papillomavirus vaccination: a retrospective case series. Stratton K, Ford A, Rusch E, Clayton EW, eds. More than half said they experienced a sore arm, fatigue or headache. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Among the 60 reports of syncope after influenza vaccine, 15 (25%) indicated that the patient had a history of syncope or needle aversion. Otol Neurotol. If these side effects occur, they should go away in a few days. Fitzsimmons W, Nance CS. Neurological complications of COVID-19: Guillain-Barre syndrome following Pfizer COVID-19 vaccine. Side Effects of COVID-19 Vaccines - WHO | World Health Organization Angiology. Crawford NW, Clothier HJ, Elia S, Lazzaro T, Royle J, Buttery JP. Ann Neurol. According to reports, these complications are more common in men and women between the ages of 20 and 60 [9]. Al Khames Aga QA, Alkhaffaf WH, Hatem TH, Nassir KF, Batineh Y, Dahham AT, Shaban D, Al Khames Aga LA, Agha MY, Traqchi M. Safety of COVID-19 vaccines. Post-COVID conditions among adult COVID-19 survivors aged 18-64 and 65 years United States, March 2020 November 2021. The process that causes the disorder is probably explained by the fact that the varicella-zoster virus CD8+killer cells, after vaccination, are temporarily unable to control VZV due to the extensive change of simple CD8+cells to the COVID-19 virus CD8+killer cells. J Neuroimmunol. de Terreros Caro GG, Daz SG, Al MP, Gimeno MM. Risk evaluation and mitigation strategies for newly detected SARSCoV2 For example, if you fear getting the vaccine because you might have an allergic reaction, consult the facts: one study of the Pfizer vaccin e showed . Finsterer J. Overall, the benefits of being vaccinated are much greater than the risks involved. Acute transverse myelitis associated with COVID-19 vaccine: a case report. QJM: An Int J Med. BMJ Case Reports CP. An unexpected COVID-19 vaccine side effect - KevinMD.com Chen S, Fan X-R, He S, Zhang J-W, Li S-J. All COVID-19 vaccine recipients should be observed for at least 15 minutes after vaccination for anxiety-related and other events (e.g., anaphylaxis or immediate allergic reaction) occurring shortly after vaccination. Ideggyogyaszati Szemle. Due to the activity of the immune system, after the injection of COVID-19 vaccines, especially adenovirus-based type, thrombocytopenia, cerebral venous sinus thrombosis, ischemic stroke and intracerebral hemorrhage, have also been reported [27]. You might run a fever and experience body aches, headaches and tiredness for a day or two. Understanding COVID-19 vaccine side effects, why second dose could feel Her PCP thought she was having a panic attack and gave her Xanax. Int Forum Allergy Rhinol. Zhang Y, Zeng G, Pan H, Li C, Hu Y, Chu K, Han W, Chen Z, Tang R, Yin W. Safety, tolerability, and immunogenicity of an inactivated SARS-CoV-2 vaccine in healthy adults aged 1859 years: a randomised, double-blind, placebo-controlled, phase 1/2 clinical trial. The sites reported 64 anxiety-related events, most of which resolved "within 15 minutes with supportive care." The most common symptoms were light-headeadness or dizziness, occurring in over 50% of. Article 2021. https://doi.org/10.1093/qjmed/hcab069. Karussis D, Petrou P. The spectrum of post-vaccination inflammatory CNS demyelinating syndromes. Cookies policy. 2021;121(4):108991. There are four major strategies for producing COVID-19 vaccines, including nucleic acid-based vaccine (DNAmRNA), viral vector (replicationnon-replication), live inactivated (or attenuated) virus, and protein (spike protein or its subunits). Int J Audiol. The most commonly reported symptoms of post-COVID-19 syndrome include: Keep in mind that it can be hard to tell if you are having symptoms due to COVID-19 or another cause, such as a preexisting medical condition. J Neurol Neurosurg Psychiatry. A review of neurological side effects of COVID-19 vaccination, https://doi.org/10.1186/s40001-023-00992-0, https://doi.org/10.1007/s10072-021-05662-9, https://doi.org/10.1038/s41598-022-17514-3, https://doi.org/10.1007/s13760-021-01775-2, https://doi.org/10.9734/ijmpcr/2021/v14i130124, https://doi.org/10.1007/s12024-021-00440-7, https://doi.org/10.1016/j.nrleng.2021.05.002, https://doi.org/10.6061/clinics/2021/e3286, https://doi.org/10.1080/14992027.2021.1931969, https://doi.org/10.1136/postgradmedj-2021-141022, https://doi.org/10.1007/s00415-021-10780-7, https://doi.org/10.1016/j.nrleng.2021.04.002, http://creativecommons.org/licenses/by/4.0/, http://creativecommons.org/publicdomain/zero/1.0/. First, VAERS is a passive surveillance reporting system and subject to underreporting (1). Source: Mass General Videos of people experiencing severe neurological symptoms, including convulsions and difficulty . Ogbebor O, Seth H, Min Z, Bhanot N. Guillain-Barr syndrome following the first dose of SARS-CoV-2 vaccine: a temporal occurrence, not a causal association. By comparison, 60 reports of syncope after receipt of influenza vaccination were identified during July 1, 2019June 30, 2020 (0.05 episodes of syncope per 100,000 doses of influenza vaccine administered). In addition, in mass vaccination situations, an anxiety-related event witnessed by others on-site or reported through media coverage might provoke additional anxiety-induced episodes (4). Thromb Res. PubMed Among the 653 VAERS reports of syncope, 327 (50%) occurred in women. Reports of syncope were approximately 164 times more common after Janssen COVID-19 vaccination (8.2 per 100,000) than after influenza vaccination (0.05 per 100,000). Loharikar A, Suragh TA, MacDonald NE, et al. O. Ozzy4335 HR MVP. "Reassuring the public that everything is being done . Burrows A, Bartholomew T, Rudd J, Walker D. Sequential contralateral facial nerve palsies following COVID-19 vaccination first and second doses. Most people who get coronavirus disease 2019 (COVID-19) recover within a few weeks. McMahon DE, Amerson E, Rosenbach M, Lipoff JB, Moustafa D, Tyagi A, Desai SR, French LE, Lim HW, Thiers BH. Most events resolved within 15 minutes with supportive care. Thirteen (20%) patients were transported to an emergency department for further medical evaluation; among these, all five for whom follow-up information was available were released from medical care on the same day.
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